Depression in X-linked dystonia-parkinsonism: A case-control study
Date
2013-09-01Author
MeSH term
Parkinson DiseaseDystonic Disorders
Genetic Diseases, X-Linked
Case-Control Studies
Depression
Dystonic Disorders
Heredodegenerative Disorders, Nervous System
Humans
Male
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Abstract
X-linked dystonia-parkinsonism (XDP), also known as lubag, was originally described as endemic to Panay, Philippines [ [1] ]. XDP demonstrates a primary and progressive neuronal degeneration of the striatum and is characterized by an adult-onset movement disorder that manifests as severe and progressive dystonia with a high frequency of generalization, followed by the onset of a parkinsonian state in the later years of life [ 1 , 2 ]. Suicide incidence has been reported to account for 9% of the mortality in patients with XDP [ [1] ]. Despite the high suicide risk, only a few case reports refer to mood disorders in patients with XDP. The purpose of this study was to determine the prevalence of depressive symptoms among patients with XDP.
Recommended Citation
Morigaki, R., Nakataki, M., Kawarai, T., Lee, L. V., Teleg, R. A., Tabuena, M. D. P., ... & Kaji, R. (2013). Depression in X-linked dystonia-parkinsonism: A case-control study.Type
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13538020Keywords
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