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dc.contributor.authorRhee, Sang Youl
dc.contributor.authorGuan, Heng
dc.contributor.authorLiu, Zhi-Min
dc.contributor.authorCheng, Stephen Wing Keung
dc.contributor.authorWaspadji, Sarwono
dc.contributor.authorPalmes, Patricio
dc.contributor.authorTai, Tong Yuan
dc.contributor.authorSuwanwalaikorn, Sompongse
dc.contributor.authorKim, Young Seol
dc.coverage.spatialKoreaen
dc.coverage.spatialChinaen
dc.coverage.spatialTaiwanen
dc.coverage.spatialHong Kongen
dc.coverage.spatialIndonesiaen
dc.coverage.spatialAsiaen
dc.coverage.spatialPilipinasen
dc.coverage.spatialPrathet Thaien
dc.date.accessioned2024-05-09T07:00:56Z
dc.date.available2024-05-09T07:00:56Z
dc.date.issued2007-04-01
dc.identifier.citationRhee, S. Y., Guan, H., Liu, Z. M., Cheng, S. W. K., Waspadji, S., Palmes, P., Tai, T. Y., Suwanwalaikorn, S. & Kim, Y. S. (2007). Multi-country study on the prevalence and clinical features of peripheral arterial disease in asian type 2 diabetes patients at high risk of atherosclerosis. Diabetes Research and Clinical Practice, 76(1), 82-92.en
dc.identifier.issn0168-8227
dc.identifier.urihttps://hdl.handle.net/20.500.14353/430
dc.description.abstractObjective: PAD-SEARCH was the first international study to investigate the prevalence of peripheral arterial disease (PAD) in Asian type 2 diabetic patients and to demonstrate the relationships between putative risk factors and PAD. Subjects and methods: In total 6625 type 2 diabetic patients aged 50 and older were enrolled and determined ankle-brachial index (ABI) and brachial-ankle pulse wave velocity (baPWV) in Korea, China, Taiwan, Hong Kong, Indonesia, Thailand and the Philippines. Results: Mean patient age was 63.7 ± 8.2 years and mean duration of diabetes was 10.3 ± 8.0 years. One thousand one hundred and seventy-two (17.7%) subjects were diagnosed as PAD by ABI (≤0.9). PAD subjects had a significantly longer duration of diabetes, hypertension, higher HbA1c, and a significantly lower mean BMI than non-PAD subjects. In terms of lipid profiles, triglyceride was the only significant variable. Notably, mean ABI and baPWV in females were significantly poorer than age matched males in subjects with a normal ABI. However, mean ABI and baPWV in males were significantly poorer than in age matched females in subjects with PAD. Conclusions: These findings suggest that PAD is a common complication in Asian type 2 diabetic patients. Therefore, PAD screening and treatment should be emphasized for Asian diabetic patients with high risk factors.en
dc.description.sponsorshipThe OIAA Co., Ltd. (Otsuka International Asia, Arab Division at Korea Otsuka Pharmaceutical Company) provided financial support for this study. Fukuda Densi Co., Ltd. were responsible for the importation and transportation of VaSera VS-1000™.en
dc.language.isoenen
dc.publisherElsevieren
dc.subjectAsiaen
dc.subjectDiabetes complicationsen
dc.subjectDiabetes mellitusen
dc.subjectEpidemiologyen
dc.subjectPeripheral vascular diseasesen
dc.subjectRisk factorsen
dc.subjectAsian peopleen
dc.subject.lcshAsiansen
dc.subject.lcshDiabetes--Complicationsen
dc.subject.lcshDiabetesen
dc.subject.lcshEpidemiologyen
dc.subject.lcshPeripheral vascular diseasesen
dc.subject.lcshDiseases--Risk factorsen
dc.subject.lcshAtherosclerosisen
dc.subject.lcshBody mass indexen
dc.subject.meshAtherosclerosisen
dc.subject.meshAsian Peopleen
dc.subject.meshDiabetes Mellitus, Type 2en
dc.subject.meshGlycated Hemoglobinen
dc.subject.meshHypertensionen
dc.subject.meshMulticenter Studies as Topicen
dc.subject.meshMultivariate Analysisen
dc.subject.meshPrevalenceen
dc.subject.meshRisk Factorsen
dc.subject.meshPeripheral Vascular Diseasesen
dc.subject.meshTriglyceridesen
dc.subject.meshPeripheral Arterial Diseaseen
dc.titleMulti-country study on the prevalence and clinical features of peripheral arterial disease in Asian type 2 diabetes patients at high risk of atherosclerosisen
dc.typeArticleen
dcterms.accessRightsLimited public accessen
dc.citation.journaltitleDiabetes Research and Clinical Practiceen
dc.citation.volume76en
dc.citation.issue1en
dc.citation.firstpage82en
dc.citation.lastpage92en
dc.identifier.essn1872-8227
dc.identifier.doi10.1016/j.diabres.2006.07.029
local.isIndexedByScopusen


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